| Bioactivity | SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism[1][2]. | ||||||
| Target | IC50: bacterial; fungal | ||||||
| Name | SMAP-29 | ||||||
| CAS | 172485-26-6 | ||||||
| Shortening | RGLRRLGRKIAHGVKKYGPTVLRIIRIAG | ||||||
| Formula | C146H260N52O32 | ||||||
| Molar Mass | 3256.02 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
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| Reference | [1]. B Skerlavaj, et al. SMAP-29: a potent antibacterial and antifungal peptide from sheep leukocytes. FEBS Lett. 1999 Dec 10;463(1-2):58-62. [2]. Rachel C Anderson, et al.Antimicrobial activity and bacterial-membrane interaction of ovine-derived cathelicidins. Antimicrob Agents Chemother |
SMAP-29
CAS: 172485-26-6 F: C146H260N52O32 W: 3256.02
SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-deriv
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