| Bioactivity | SM-433 hydrochlorid, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 hydrochlorid exhibits strong binding affinity XIAP BIR3 protein with an IC50<1 μM (patent WO2008128171A2)[1]. |
| Invitro | SM-433 hydrochlorid exhibits strong inhibitory activity against MDA-MB -2131 human breast cancer cells and SK-OV-3 ovarian cancer cells (IC50s<10 μM, respectively)[1]. |
| Name | SM-433 hydrochloride |
| Formula | C32H44ClN5O4 |
| Molar Mass | 598.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
SM-433 hydrochloride
CAS: F: C32H44ClN5O4 W: 598.18
SM-433 hydrochlorid, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 hydrochlori
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