PeptideDB

SM-102

CAS: 2089251-47-6 F: C44H87NO5 W: 710.17

SM-102 is an ionizable amino lipid that can be used for the formation of lipid nanoparticles (LNPs). SM-102 has the pote
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Bioactivity SM-102 is an ionizable amino lipid that can be used for the formation of lipid nanoparticles (LNPs)[1]. SM-102 has the potential for development of lipid nanoparticles for delivery of mRNA-based vaccines[2].
Name SM-102
CAS 2089251-47-6
Formula C44H87NO5
Molar Mass 710.17
Appearance Liquid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Staci Sabnis, et al. A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates. Mol Ther. 2018 Jun 6;26(6):1509-1519. [2]. Without these lipid shells, there would be no mRNA vaccines for COVID-19