| Bioactivity | SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM[1]. SL 0101-1 (SL0101) is a selective RSK1/2 inhibitor, with a Ki of 1 μM[2]. | ||||||||||||
| Invitro | SL 0101-1 (SL0101) shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase[1]. | ||||||||||||
| Name | SL 0101-1 | ||||||||||||
| CAS | 77307-50-7 | ||||||||||||
| Formula | C25H24O12 | ||||||||||||
| Molar Mass | 516.45 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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