| Bioactivity | SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. SKF-75670 hydrochloride is also a Cocaine antagonist[1][2][3]. |
| In Vivo | SKF-75670 hydrochloride (2.5-10 mg/kg，腹腔注射) 降低 MPTP 处理的狨猴的运动活性[2]。SKF-75670 hydrochloride (0.3 和 1.0 mg/kg，肌肉注射) 拮抗可卡因对猴子的速率改变和辨别刺激作用[3]。 Animal Model: |
| Name | SKF-75670 hydrobromide |
| CAS | 62717-63-9 |
| Formula | C17H20BrNO2 |
| Molar Mass | 350.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rosenzweig-Lipson S, et al. Dopamine D1 receptor involvement in the discriminative-stimulus effects of SKF 81297 in squirrel monkeys. J Pharmacol Exp Ther. 1993 Nov;267(2):765-75. [2]. Gnanalingham KK, et al. Differential anti-parkinsonian effects of benzazepine D1 dopamine agonists with varying efficacies in the MPTP-treated common marmoset. Psychopharmacology (Berl). 1995 Feb;117(3):275-86. [3]. Spealman RD, et al. Differential modulation of behavioral effects of cocaine by low- and high-efficacy D1 agonists. Psychopharmacology (Berl). 1997 Oct;133(3):283-92. |
SKF-75670 hydrobromide
CAS: 62717-63-9 F: C17H20BrNO2 W: 350.25
SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. SKF-75670 hydrochloride is also a Cocaine antagonist.
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This product is for research use only, not for human use. We do not sell to patients.