| Bioactivity | SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis[1]. |
| CAS | 126053-71-2 |
| Sequence | Ac-Cys-{(NMe)Arg}-Gly-Asp-{Pen}-NH2 (Disulfidebridge:Cys1-Pen5) |
| Shortening | Ac-C-{(NMe)Arg}-GD-{Pen}-NH2 (Disulfidebridge:Cys1-Pen5) |
| Formula | C23H39N9O8S2 |
| Molar Mass | 633.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis |
SKF 106760
CAS: 126053-71-2 F: C23H39N9O8S2 W: 633.74
SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and ant
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