| Bioactivity | SJ6145 is a potent ligand for KLHDC2SBD, with the Kd of 16.9 μM in SPR test, IC50 value of 42 μM in inhibiting KLHDC2SBD binding to a di-Gly degron peptide test[1]. |
| CAS | 1010913-79-7 |
| Formula | C13H11FN2O3S |
| Molar Mass | 294.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Daniel C Scott, et al. Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2. Nat Commun. 2024 Oct 12;15(1):8829. doi: 10.1038/s41467-024-52966-3. |