Bioactivity | SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM, inhibits the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs[1]. | ||||||
Name | SIS17 | ||||||
CAS | 2374313-54-7 | ||||||
Formula | C21H38N2OS | ||||||
Molar Mass | 366.60 | ||||||
Appearance | Solid | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage |
*该产品在溶液状态不稳定,建议您现用现配,即刻使用。 |
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Reference | [1]. Son SI, et al. Activity-Guided Design of HDAC11-Specific Inhibitors. ACS Chem Biol. 2019 Jul 19;14(7):1393-1397. |