Bioactivity | SIRT5 inhibitor 8 (compound 10) is a competitive inhibitor (IC50: 5.38 μM) of sirtuin SIRT5 with anticancer potential[1]. |
Target | IC50: 5.38 μM (SIRT5) |
Name | SIRT5 inhibitor 8 |
Formula | C22H25ClN8O2S |
Molar Mass | 501.00 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang L, et al. Design, synthesis and biological evaluation of 2,4,6- trisubstituted triazine derivatives as new nonpeptide small-molecule SIRT5 inhibitors. Bioorg Med Chem. 2023 Oct 1;93:117455.. . |