| Bioactivity | SIRT1-IN-4 (Compound 8c) is a SIRT1 inhibitor, with an IC50 of 10.04 μM. SIRT1-IN-4 can be used for the research of cancer[1]. |
| CAS | 445405-18-5 |
| Formula | C25H18O7 |
| Molar Mass | 430.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li C, et al. Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors. ACS Med Chem Lett. 2021 Mar 1;12(3):397-403. |