Bioactivity | SHP389 is an allosteric SHP2 inhibitor, with an IC50 of 36 nM for both SHP2 and p-ERK[1]. | ||||||||||||
Target | IC50: 36 nM (SHP2 and p-ERK). | ||||||||||||
In Vivo | SHP389 modulates MAPK signaling in vivo[1]. | ||||||||||||
Name | SHP389 | ||||||||||||
CAS | 2235394-90-6 | ||||||||||||
Formula | C23H29ClN8O2 | ||||||||||||
Molar Mass | 484.98 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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