| Bioactivity | SHP2-IN-32 (compound C6) is an orally active, allosteric SHP2 inhibitor with an IC50 value of 0.13 nM. SHP2-IN-32 exhibits antitumor activity[1]. |
| Target | IC50:0.13 nM (SHP2). |
| CAS | 3043685-80-6 |
| Formula | C29H27ClN6O2S |
| Molar Mass | 559.08 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lv X, et al. Discovery of novel substituted pyridine carboxamide derivatives as potent allosteric SHP2 inhibitors. Eur J Med Chem. 2024 Sep 5;279:116830. |
SHP2-IN-32
CAS: 3043685-80-6 F: C29H27ClN6O2S W: 559.08
SHP2-IN-32 (compound C6) is an orally active, allosteric SHP2 inhibitor with an IC50 value of 0.13 nM. SHP2-IN-32 exhibi
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