Bioactivity | SHP2-IN-24 (compound 111675) is a potent SHP2 inhibitor with an IC50 value of 0.878 µM and a Ki value of 0.118 µM[1]. |
Target | IC50:0.878 µM(SHP2) |
Name | SHP2-IN-24 |
Formula | C23H22ClN5O4S |
Molar Mass | 499.97 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mitra R, et al. Identification of new small molecule allosteric SHP2 inhibitor through pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation studies, synthesis and in vitro evaluation. J Biomol Struct Dyn. 2023 Dec 14:1-20. |