Bioactivity | SGS518 oxalate is a selective 5-HT6R antagonist. SGS518 oxalate can be used for the research of cognitive impairments such as amnesia, anxiety and depression, and it is effective in protecting mouse retina at high doses[1] |
In Vivo | SGS518 oxalate (30 mg/kg; i.p. for 30 min) protects Abca4–/–Rdh8 sup>–/– mouse retinas from light-induced damage[1]. Animal Model: |
Name | SGS518 oxalate |
CAS | 445441-27-0 |
Formula | C23H24F2N2O7S |
Molar Mass | 510.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chen Y, et, al. Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration. J Clin Invest. 2013 Dec; 123(12): 5119-34. |