| Bioactivity | SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1]. |
| Target | IC50: 43 nM (hSGLT1), 9 nM (hSGLT2) |
| Name | SGLT inhibitor-1 |
| CAS | 2247314-23-2 |
| Formula | C24H27FO8 |
| Molar Mass | 462.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu G， et al. Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3446-3453. |
SGLT inhibitor-1
CAS: 2247314-23-2 F: C24H27FO8 W: 462.46
SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT
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