| Bioactivity | SGC6870 is a potent, selective and cytoactive allosteric inhibitor of PRMT6 with IC50 of 77 nM[1]. |
| Target | IC50: 77 nM (PRMT6). |
| Name | SGC6870 |
| CAS | 2561471-27-8 |
| Formula | C23H21BrN2O2S |
| Molar Mass | 469.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shen Y, et al. A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6. J Med Chem. 2021 Apr 8;64(7):3697-3706. doi: 10.1021/acs.jmedchem.0c02160. Epub 2021 Feb 16. PMID: 33591753; PMCID: PMC8035306. |