| Bioactivity | SGC agonist 2 is a potent agonist of soluble guanylate cyclase (SGC). Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031)[1]. |
| Name | SGC agonist 2 |
| CAS | 2735713-77-4 |
| Formula | C23H17F2N7O2 |
| Molar Mass | 461.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fuyu Luo, et al. Pyrimidine tricyclic compounds and their applications. Patent WO2021219088A1. |
SGC agonist 2
CAS: 2735713-77-4 F: C23H17F2N7O2 W: 461.42
SGC agonist 2 is a potent agonist of soluble guanylate cyclase (SGC). Soluble guanylate cyclase is a key signal transduc
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