Bioactivity | SGA360 suppress inflammatory SAA1 signaling in an AHR-dependent manner through a mechanism that does not require AHR binding to its cognate response element (partial antagonist)[1]. |
In Vivo | SGA360 exhibits anti-inflammatory activity in vivo. |
Name | SGA360 |
CAS | 680611-86-3 |
Formula | C19H17F3N2O2 |
Molar Mass | 362.35 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Iain A Murray, et al. Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties. Chem Res Toxicol. 2010 May 17;23(5):955-66. |