| Bioactivity | SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.) |
| Name | SFNGGP-NH2 |
| CAS | 261521-21-5 |
| Sequence | Ser-Phe-Asn-Gly-Gly-Pro-NH2 |
| Shortening | SFNGGP-NH2 |
| Formula | C25H36N8O8 |
| Molar Mass | 576.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
SFNGGP-NH2
CAS: 261521-21-5 F: C25H36N8O8 W: 576.60
SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the c
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