| Bioactivity | SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of ＜200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer[1]. |
| Invitro | SF-1 antagonist-1 (0-20 μM) affects SF-1 transcriptional activity with an EC50 value of ＜200 nM[1].SF-1 antagonist-1 (0-20 μM; 48 h) affects proliferation of R2C cells[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | SF-1 antagonist-1 |
| CAS | 2842079-86-9 |
| Formula | C22H18F4N6O3 |
| Molar Mass | 490.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Raheja Neil, et al. PYRAZOLOPYRIMIDINONE COMPOUNDS. WO2022204481. 2022. |
SF-1 antagonist-1
CAS: 2842079-86-9 F: C22H18F4N6O3 W: 490.41
SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcr
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