| Bioactivity | SENP2-IN-1 (compound 77) is a selective SENP2 inhibitor. SENP2-IN-1 shows inhibitory activities with IC50s of 1.3, 0.69 and 22.7 μM for SENP1, SENP2 and SENP5, respectively. SENP2-IN-1 can be used for the research of cancer[1]. |
| Target | IC50: 1.3 μM (SENP1), 0.69 μM (SENP2), 22.7 μM (SENP5) |
| Invitro | SENP2-IN-1 (0.78-100 µM; 10 min) inhibits activities of SENP1, SENP2 and SENP5 with IC50 values of 1.3, 0.69 and 22.7 μM, respectively[1]. |
| Name | SENP2-IN-1 |
| Formula | C32H29N3O5S2 |
| Molar Mass | 599.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang Z, et al. Benzothiophene-2-carboxamide derivatives as SENPs inhibitors with selectivity within SENPs family. Eur J Med Chem. 2020 Oct 15;204:112553. |