| Bioactivity | SEN 304 is an Aβ aggregation inhibitor. SEN 304 can bind directly to Aβ(1-42), delay β-sheet formation and promote aggregation of toxic oligomers into a nontoxic form. SEN 304 can be used for research of Alzheimer’s disease[1]. |
| Sequence | D-{{Chg}-Tyr-{Chg}-{Chg}-{N(Me)-Leu}-NH2} |
| Shortening | D-{{Chg}-Y-{Chg}-{Chg}-{N(Me)-Leu}-NH2} |
| Formula | C40H64N6O6 |
| Molar Mass | 724.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Amijee H, et al. The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation. Biochemistry. 2012 Oct 23;51(42):8338-52. |