Bioactivity | SDZ-WAG994 (WAG-994) is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation[1]. |
Target | KD: 23 nM (A1-adenosine receptor) |
Name | SDZ-WAG994 |
CAS | 130714-47-5 |
Formula | C17H25N5O4 |
Molar Mass | 363.41 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. O Piot, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21(11 Pt 2):2459-64. [2]. Wagner H, et al. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist. Drug development research, 1995, 34(3): 276-288. [3]. Piot O, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21(11 Pt 2):2459-64. |