PeptideDB

SDZ 216-525

CAS: 141533-35-9 F: C25H28N4O5S W: 496.58

SDZ 216-525 is a selective silent antagonist of 5-HT1A receptor.
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Bioactivity SDZ 216-525 is a selective silent antagonist of 5-HT1A receptor[1][2].
CAS 141533-35-9
Formula C25H28N4O5S
Molar Mass 496.58
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Boddeke H W G M, et al. Agonist/antagonist interactions with cloned human 5-HT 1A receptors: variations in intrinsic activity studied in transfected HeLa cells[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1992, 345: 257-263. [2]. Sharp T, et al. The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo[J]. British journal of pharmacology, 1993, 109(3): 699-702.