Bioactivity | SDM25N hydrochloride, a δ-opioid receptor antagonist, is a potent DENV inhibitor. SDM25N hydrochloride targets the viral NS4B protein and restricts genomic RNA replication[1]. |
Invitro | SDM25N hydrochloride (1-25 µM) 在 Hela 和 BHK-21 细胞中均显示出对野生型 DENV2 的抗病毒活性,但在源自白纹伊蚊的 C6/36 细胞系中则无此活性[1]。SDM25N hydrochloride 限制的是基因组 RNA 复制,而不是病毒基因组的翻译[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> SDM25N hydrochloride 相关抗体: |
CAS | 342884-71-3 |
Formula | C26H27ClN2O3 |
Molar Mass | 450.96 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Koen W R van Cleef, et al. Identification of a new dengue virus inhibitor that targets the viral NS4B protein and restricts genomic RNA replication. Antiviral Res. 2013 Aug;99(2):165-71. |