| Bioactivity | SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC50 value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC50 value of 0.23 μg/mL[1]. |
| Invitro | SDH-IN-4 (10 μg/mL， 3-5 天) 显著抑制真菌 R. solani， F. graminearum， B. cinerea 和 A. solani 菌丝生长[1]。 |
| In Vivo | SDH-IN-4 (100 μg/mL， 5 天) 在水稻离体叶片中对 R. solani 的抑制率为87.48%[1]。SDH-IN-4 (20 μg/mL， 0.5-3 小时) 抑制菌丝 R. solani 生长发育并严重破坏菌丝细胞膜[1]。 |
| Name | SDH-IN-4 |
| Formula | C11H9Cl2F3N4O2S |
| Molar Mass | 389.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chai JQ, et al. Potential Succinate Dehydrogenase Inhibitors Bearing a Novel Pyrazole-4-sulfonohydrazide Scaffold: Molecular Design, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2023 Jun 21;71(24):9266-9279. |