| Bioactivity | SDH-IN-15 (Compound 5e) is an inhibitor of succinate dehydrogenase (SDH) (IC50=2.04 μM). SDH-IN-15 has significant antifungal activity. SDH-IN-15 blocks the mitochondrial respiratory chain of the fungus through inhibition of SDH, resulting in fungal death[1]. |
| Invitro | SDH-IN-15 的抗真菌活性分别为 EC50=0.039 μg/mL (R. solani); 0.426 μg/mL (S. sclerotiorum); 3.482 μg/mL (B. cinerea) 。优于 Boscalid (HY-119976) 和 Fluxapyroxad (HY-135549)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> SDH-IN-15 相关抗体: |
| In Vivo | SDH-IN-15 (100 μg/mL; 5 天) 对水稻叶片上的立枯丝核菌的生长具有显著的抑制效果，保护效率达 86.8 %，明显优于对照药物 Boscalid (HY-119976) (68.1 %) 和 Fluxapyroxad (HY-135549) (80.6 %)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C21H19BrF2N4O2 |
| Molar Mass | 477.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Luo B, et al. Novel Pyrazole-4-Carboxamide Derivatives Containing Oxime Ether Group as Potential SDHIs to Control Rhizoctonia solani. J Agric Food Chem. 2024 May 1;72(17):9599-9610. |