Bioactivity | SDGR is a Ser-Asp-Gly-Arg tetrapeptide sequence that effectively inhibits fibronectin-mediated cell attachment[1] |
Invitro | SDGR (0-500 μg/mL) can inhibit spreading of BHK cells or chick embryo fibroblasts on human spreading factor (vitronectin)-coated substrates and chick embryo fibroblasts are more sensitive to SDGR inhibition. Meanwhile, it can inhibit spreading of them on laminin(50 μg/mL)-coated substrates[1]. |
Name | SDGR |
CAS | 97461-82-0 |
Shortening | SDGR |
Formula | C15H27N7O8 |
Molar Mass | 433.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yamada KM, et al. Peptide inhibitors of fibronectin, laminin, and other adhesion molecules: unique and shared features. J Cell Physiol. 1987 Jan;130(1):21-8. |