| Bioactivity | SBI-810 hydrochloride is a functionally selected β-arrestin-biased neurotensin receptor 1 (NTSR1) allosteric modulator. SBI-810 hydrochloride modulates NTSR1 G protein signaling in a G protein-specific manner in the presence of the endogenous ligand, neurotensin (NT). SBI-810 hydrochloride fully antagonizes NT-induced activation of Gq, partially antagonizes NT-induced activation of Gi1 and is permissive of NTSR1 activation of GoA and G12[1][2]. |
| CAS | 2772746-58-2 |
| Formula | C27H35ClN4O2 |
| Molar Mass | 483.05 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Lawrence Barak, et al. Compositions for and methods of treating and/or preventing pain. WO2022241186A1. 2022 November 17. [2]. Center M N A, et al. Summer Undergraduate Research Expo[J]. 2014. |
SBI-810 hydrochloride
CAS: 2772746-58-2 F: C27H35ClN4O2 W: 483.05
SBI-810 hydrochloride is a functionally selected β-arrestin-biased neurotensin receptor 1 (NTSR1) allosteric modulator.
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.