Bioactivity | SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM[1]. | ||||||||||||
Name | SBI-553 | ||||||||||||
CAS | 1849603-72-0 | ||||||||||||
Formula | C26H31FN4O2 | ||||||||||||
Molar Mass | 450.55 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Pinkerton AB, et al. Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. J Med Chem. 2019 Aug 20. |