| Bioactivity | SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1, Figure 1. | ||||||||||||
| In Vivo | SBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels[1]. | ||||||||||||
| Name | SBC-110736 | ||||||||||||
| CAS | 1629166-02-4 | ||||||||||||
| Formula | C26H27N3O2 | ||||||||||||
| Molar Mass | 413.51 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Sherin Salaheldin Abdel-Meguid, et al. Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases. WO2014150395A1. |
SBC-110736
CAS: 1629166-02-4 F: C26H27N3O2 W: 413.51
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1, Fi
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