| Bioactivity | SB1617 is a neuroinflammation-modulating agent, and has neuroprotective effect by reducing pathogenic tau levels through microglia-mediated anti-inflammatory activity[1][2]. |
| Name | SB1617 |
| Formula | C22H21ClN6O5S |
| Molar Mass | 516.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cho H, et al. Neuroinflammation-Modulating Agent SB1617 Enhances LC3-Associated Phagocytosis to Mitigate Tau Pathology. ACS Chem Neurosci. 2023;14(23):4139-4152. [2]. Shin YH, et al. Phenotypic Discovery of Neuroprotective Agents by Regulation of Tau Proteostasis via Stress-Responsive Activation of PERK Signaling. Angew Chem Int Ed Engl. 2021;60(4):1831-1838. doi:10.1002/anie.202013915 |