| Bioactivity | SB-706375 is an antagonist of the Urotensin II (UII) receptor. By blocking the Urotensin II receptor, SB-706375 reduces the kidney's response to UII and Urotensin-related peptide (URP) and significantly increases the Glomerular Filtration Rate (GFR). SB-706375 can be used in research on kidney diseases and hypertension[1]. |
| CAS | 733734-61-7 |
| Formula | C20H22BrF3N2O5S |
| Molar Mass | 539.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Forty E J, et al. The urotensin system is up-regulated in the pre-hypertensive spontaneously hypertensive rat[J]. PLoS One, 2013, 8(12): e83317. |
SB-706375
CAS: 733734-61-7 F: C20H22BrF3N2O5S W: 539.36
SB-706375 is an antagonist of the Urotensin II (UII) receptor. By blocking the Urotensin II receptor, SB-706375 reduces
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