| Bioactivity | SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 15.4 and 133.2 nM; and IC90s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities[1]. | ||||||||||||
| Invitro | SARS-CoV-IN-1 (Compound 2) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ) [1]. | ||||||||||||
| Name | SARS-CoV-IN-1 | ||||||||||||
| CAS | 888958-25-6 | ||||||||||||
| Formula | C23H16ClFeN3O | ||||||||||||
| Molar Mass | 441.69 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Biot C, et al. Design and synthesis of hydroxyferroquine derivatives with antimalarial and antiviral activities. J Med Chem. 2006 May 4;49(9):2845-9. |
SARS-CoV-IN-1
CAS: 888958-25-6 F: C23H16ClFeN3O W: 441.69
SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an E
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