| Bioactivity | SARS-CoV-2 nsp14-IN-4 (Compound 12q) is an inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50=19 nM). SARS-CoV-2 nsp14-IN-4 is non-cytotoxic and cell-permeable. SARS-CoV-2 nsp14-IN-4 is used in COVID-19 research[1]. |
| Target | IC50: 19 nM (SARS-CoV-2 nsp14 methyltransferase) |
| Invitro | SARS-CoV-2 nsp14-IN-4 (5 μM，60 分钟) 在小鼠和人的微粒体中显示出优异的稳定性[1]。 0 --> SARS-CoV-2 nsp14-IN-4 相关抗体: |
| Name | SARS-CoV-2 nsp14-IN-4 |
| Formula | C31H27N7O6S |
| Molar Mass | 625.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Štefek M, et al. Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors. ACS Omega. 2023 Jul 21;8(30):27410-27418. |
SARS-CoV-2 nsp14-IN-4
CAS: F: C31H27N7O6S W: 625.65
SARS-CoV-2 nsp14-IN-4 (Compound 12q) is an inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50=19 nM). SARS-CoV-2 nsp1
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