| Bioactivity | SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research[1]. |
| Target | IC50: 6 ± 0.5 μM (nsp13 ssDNA+ ATPase) |
| Name | SARS-CoV-2 nsp13-IN-1 |
| CAS | 1005304-44-8 |
| Formula | C27H20N4O2 |
| Molar Mass | 432.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13. |
SARS-CoV-2 nsp13-IN-1
CAS: 1005304-44-8 F: C27H20N4O2 W: 432.47
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only
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