Bioactivity | SARS-CoV-2 Mpro-IN-13 (compound 20j) is a covalent SARS-CoV-2 Protease Mpro inhibitor with an IC50 value of 19.0 nM. SARS-CoV-2 Mpro-IN-13 processes antiviral activity with an EC50 value of 138.1 nM[1]. |
Target | IC50:19.0 nM (Mpro) |
Invitro | SARS-CoV-2 Mpro-IN-13 抑制 Mpro 的活性,IC50是19.0 nM[1]。SARS-CoV-2 Mpro-IN-13 抑制 SARS-CoV-2 在HPAEpiC 细胞中的复制,EC50是138.1 nM [1]。 0 --> SARS-CoV-2 Mpro-IN-13 相关抗体: |
Name | SARS-CoV-2 Mpro-IN-13 |
Formula | C29H41F2N5O6S |
Molar Mass | 625.73 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Huang Q,et al. Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups. Bioorg Chem. 2023 Dec 6;143:107001. [2]. Qiao Huang, et al. Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups. Bioorg Chem. 2023 Dec 6:143:107001. |