PeptideDB

SARS-CoV-2 Mpro-IN-13

CAS: F: C29H41F2N5O6S W: 625.73

SARS-CoV-2 Mpro-IN-13 (compound 20j) is a covalent SARS-CoV-2 Protease Mpro inhibitor with an IC50 value of 19.0 nM. SAR
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Bioactivity SARS-CoV-2 Mpro-IN-13 (compound 20j) is a covalent SARS-CoV-2 Protease Mpro inhibitor with an IC50 value of 19.0 nM. SARS-CoV-2 Mpro-IN-13 processes antiviral activity with an EC50 value of 138.1 nM[1].
Target IC50:19.0 nM (Mpro)
Invitro SARS-CoV-2 Mpro-IN-13 抑制 Mpro 的活性,IC50是19.0 nM[1]。SARS-CoV-2 Mpro-IN-13 抑制 SARS-CoV-2 在HPAEpiC 细胞中的复制,EC50是138.1 nM [1]。 0 --> SARS-CoV-2 Mpro-IN-13 相关抗体:
Name SARS-CoV-2 Mpro-IN-13
Formula C29H41F2N5O6S
Molar Mass 625.73
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Huang Q,et al. Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups. Bioorg Chem. 2023 Dec 6;143:107001. [2]. Qiao Huang, et al. Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups. Bioorg Chem. 2023 Dec 6:143:107001.