Bioactivity | SARS-CoV-2-IN-58 (Compound 21H) is an antiviral agent against SARS-CoV-2 (EC50: 18 μM). SARS-CoV-2-IN-58 inhibits SARS-CoV-2 Mpro with an IC50 of 0.35 μM[1]. |
Target | 0.35 μM (Mpro) |
Name | SARS-CoV-2-IN-58 |
Formula | C21H23ClFN5O4 |
Molar Mass | 463.89 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kang KM, et al. Discovery of antiviral SARS-CoV-2 main protease inhibitors by structure-guided hit-to-lead optimization of carmofur. Eur J Med Chem. 2023 Nov 15;260:115720. |