Bioactivity | SARS-CoV-2-IN-51 (S-10) is a potent lead compound of Omicron fusion inhibitor. SARS-CoV-2-IN-51 inhibits Omicron and other variants with EC50s of 0.82-5.45 μM. SARS-CoV-2-IN-51 inhibits SARS-CoV-2 virus entry, by the direct interaction with S in the prefusion state[1]. |
Target | SARS-CoV-2 |
Name | SARS-CoV-2-IN-51 |
Formula | C58H85NO14 |
Molar Mass | 1020.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liu M, et al. Optimization, and biological evaluation of 3-O-尾-chacotriosyl betulinic acid amide derivatives as novel small-molecule Omicron. Eur J Med Chem. 2023 Aug 5;256:115463. |