| Bioactivity | SARS-CoV-2 3CLpro-IN-27 (Compound 9H) is an inhibitor of SARS-CoV-2 3CLpro with an IC50 value of 21 nM. SARS-CoV-2 3CLpro-IN-27 exhibits excellent anti-SARS-CoV-2 replicon activity, demonstrating an EC50 value of 5 nM[1]. |
| Target | IC50: 21 nM (SARS-CoV-2 3CLpro). |
| Formula | C29H27F4N5O4 |
| Molar Mass | 585.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guma S D, et al. Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2[J]. European Journal of Medicinal Chemistry, 2024: 117004. |
SARS-CoV-2 3CLpro-IN-27
CAS: F: C29H27F4N5O4 W: 585.55
SARS-CoV-2 3CLpro-IN-27 (Compound 9H) is an inhibitor of SARS-CoV-2 3CLpro with an IC50 value of 21 nM. SARS-CoV-2 3CLpr
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