| Bioactivity | SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active SARS-CoV-2 3CLpro inhibitor. SARS-CoV-2 3CLpro-IN-14 shows significant anti-SARS-CoV-2 activity (EC50 = 0.18 μM) and low cytotoxicity (CC50 > 50 μM) in Vero E6 cells[1]. |
| Target | SARS-CoV-2 |
| Name | SARS-CoV-2 3CLpro-IN-14 |
| Formula | C34H40F3N5O6S2 |
| Molar Mass | 735.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang H, et al. Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2. Eur J Med Chem. 2023 Sep 5;257:115512. |
SARS-CoV-2 3CLpro-IN-14
CAS: F: C34H40F3N5O6S2 W: 735.84
SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active SARS-CoV-2 3CLpro inhibitor. SARS-CoV-2 3CLpro-IN-14 shows si
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