Bioactivity | SARS-CoV-2 3CLpro-IN-11(11d) is a potent SARS-CoV-2 3CL protease inhibitor with an IC50 value of 140 nM, while acting at the IC50 values of 240 nM for SARS-CoV-1 and 70 nM for MERS-CoV. SARS-CoV-2 3CLpro- IN-11 has broad-spectrum antiviral activity[1]. |
Name | SARS-CoV-2 3CLpro-IN-11 |
Formula | C25H36N3NaO9S |
Molar Mass | 577.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chamandi S., et al. Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies.ACS Pharmacol. Transl. Sci. 2023, 6, 1, 181-194 |