| Bioactivity | SAR441255 is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 displays high potency with balanced activation of all three target receptors.?SAR441255 shows positive acute glucoregulatory effectss in diabetic obese monkeys[1]. |
| Target | IC50: GLP-1/GIP/GCG receptor |
| Name | SAR441255 |
| Shortening | H-Aib-HGTFTSDLSKL-K(γGlu-γGlu-Palm acid)-EEQRQ-AibEFIEWLKA-dAla-GPPS-Aib-KPPPK-NH2 |
| Formula | C206H323N51O66 |
| Molar Mass | 4570.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Martin Bossart, et al. Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. Cell Metab. 2022 Jan 4;34(1):59-74.e10. |