| Bioactivity | SAR156497 (compound 47) is an Aurora inhibitor, with IC50 values of 0.6 nM and 1 nM for Aurora A and Aurora B, respectively. SAR156497 can also inhibit PDE3, with b>IC50 value of 4 μM. SAR156497 can be used in anticancer research[1]. |
| CAS | 1256137-14-0 |
| Formula | C27H24N4O4 |
| Molar Mass | 468.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Carry JC, et al. SAR156497, an exquisitely selective inhibitor of aurora kinases. J Med Chem. 2015 Jan 8;58(1):362-75. |