| Bioactivity | SAR107375 is a potent and orally active dual thrombin and factor Xa inhibitor, with Ki values of 1 nM and 8 nM for factor Xa and thrombin, respectively[1]. |
| Target | Ki: 1 nM (thrombin), 8 nM (factor Xa). |
| Name | SAR107375 |
| CAS | 1184300-63-7 |
| Formula | C24H30ClN5O5S2 |
| Molar Mass | 568.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jerome Meneyrol, et al. 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor. J Med Chem. 2013 Dec 12;56(23):9441-56. |
SAR107375
CAS: 1184300-63-7 F: C24H30ClN5O5S2 W: 568.11
SAR107375 is a potent and orally active dual thrombin and factor Xa inhibitor, with Ki values of 1 nM and 8 nM for facto
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