| Bioactivity | SAR107375-d11 (Tartrate) is deuterium labeled SAR107375. SAR107375 is a potent and orally active dual thrombin and factor Xa inhibitor, with Ki values of 1 nM and 8 nM for factor Xa and thrombin, respectively[1][2]. |
| Formula | C28H25D11ClN5O11S2 |
| Molar Mass | 729.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Jerome Meneyrol, et al. 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor. J Med Chem. 2013 Dec 12;56(23):9441-56. |
SAR107375-d11 Tartrate
CAS: F: C28H25D11ClN5O11S2 W: 729.26
SAR107375-d11 (Tartrate) is deuterium labeled SAR107375. SAR107375 is a potent and orally active dual thrombin and facto
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