| Bioactivity | SA-15-P inhibits LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 values of 4.21 and 6.52 μM respectively. LAG-3/MHCII interaction is a target for next-generation immunotherapies[1]. |
| CAS | 852846-00-5 |
| Formula | C26H24N2O4 |
| Molar Mass | 428.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Abdel-Rahman SA, et al. Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3). ACS Med Chem Lett. 2023 Apr 11;14(5):629-635. |