Bioactivity | S1P1 agonist 4 has a better profile in both potency (EC50 < 0.05 mg/kg) and predicted human half-life (t1/2 ∼ 5 days). |
Name | S1P1 agonist 4 |
CAS | 1883345-11-6 |
Formula | C24H31NO3 |
Molar Mass | 381.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xiao Z, et al. Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P1) Modulators: Optimization of the PK, PD, and Safety Profiles. ACS Med Chem Lett. 2020 Aug 11;11(9):1766-1772. |