| Bioactivity | S1H, a mimetic of hGH, is a human growth hormone receptor (hGHR) antagonist. S1H inhibits the interaction of hGH with hGHR. S1H inhibits phosphorylation of STAT5 in cells co-treated with hGH[1]. |
| Sequence | Ac-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-Phe-Leu-Gln-Asn-Pro-Gln-Thr-NH2 |
| Shortening | Ac-YIPKEQKYSFLQNPQT-NH2 |
| Formula | C94H141N23O27 |
| Molar Mass | 2025.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Basu R, et al. A novel peptide antagonist of the human growth hormone receptor. J Biol Chem. 2021 Jan-Jun;296:100588. |