| Bioactivity | S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase[1][2]. |
| Invitro | S-Hexylglutathione is bound by human glutathione transferase P1-1 with Kd values of 3.7 μM (Y49F mutant) and 1.27 μM (wild-type), respectively[1]. |
| Name | S-Hexylglutathione |
| CAS | 24425-56-7 |
| Formula | C16H29N3O6S |
| Molar Mass | 391.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ortiz-Salmerón E, et al. Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione. J Biol Chem. 2003 Nov 21;278(47):46938-48. [2]. Swope MD, et al. Macrophage migration inhibitory factor interactions with glutathione and S-hexylglutathione. J Biol Chem. 1998 Jun 12;273(24):14877-84. |
S-Hexylglutathione
CAS: 24425-56-7 F: C16H29N3O6S W: 391.48
S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group
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